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etrebelle PLA(Poly Lactic Acid) + HA(Sodium Hyaluronate)

The hybrid polymer filler
etrebell is a hybrid product of PLA fine particles and HA.
It simultaneously improves wrinkles and volume by creates new tissues in lost skin tissue.

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Ingredients

  • PLA(Poly Lactic Acid)
    biodegradable, biocompatible polymer
    Promotor action of new collagen production
    It is finally decomposed into H2O and CO2 by metabolism in the body
    and is discharged out of the body through the lungs and kidneys.
    HA(Sodium Hyaluronate)
    biodegradable, biocompatible polymer
    Natural polymer polysaccharides present in human body.
    Bio-compatible HA is used as cross-linking agent instead of CMC,
    a chemical reactant substance used in existing products.

Benefits of PLA microparticle

    • With promotion of collagen production,
      it maintains natural volume for more than 2 years.
    • No mobility to surrounding tissues outside the treated area.
    • No clogging on injection with spherical particles.
    • Smooth shooting with lubrication of HA.
    • Reduced procedure time due to faster suspension time.
    • It completely decomposed in the human body
      after a certain period of time with Biodegradable, bioabsorbable.

  • < Inner particle >
    Porous, Reticular structure

Animal Clinical Study Results

The formation of collagen means that a new tissue is formed. A new tissue is formed between the PLA particles and the particles, and the cells move into the PLA particles as a porous structure, forming a new tissue. It replaces the volume occupied by PLA and forms new tissue and increases the volume of skin tissue.

  • Histological analysis : H&E stain
    · A number of nuclei were observed due to the promotor action of collagen production between the Microparticles.

  • Histological analysis : Masson’s trichrome stain
    · Collagen density between Microparticles is dense and regularly observed.
    · Microparticle promotes new collagen production and increases collagen.

  • Product Name etrebell
  • Item Name Tissue Repair Material, B04230.02(4)
  • Classification Disposable medical devices, Prohibition of reuse.
  • Ingredient
    Information     Polylactide, Hyalruronic acid
  • Intended Use It is used to temporarily improve wrinkles of the face of an adult through physical repair by injecting Polyactide and hyaluronic acid under the skin.
  • Storage Store in a cool, dry room temperature (below 1 ~ 30 ℃) with unopened package.
  • Packaging Unit 200mg / vial
  • Manufacturing·
    import classification     Manufacturing: VIME Co Ltd.
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